Abstract: Due to environmental requirements, it is hoped that hydrogen can serve as the carrier for future energy supply in the industry, so as to reduce the use of fossil fuels in transportation and power generation. Economically, pipeline transportation is currently the best way to transport hydrogen over long distance and in large capacity. However, this approach faces a major dilemma, namely there is a general lack of infrastructure suitable for hydrogen pipeline transportation. As a result, the existing natural gas pipeline network may be used for transmission by enriched with compressed natural gas. In this research, the sources worked out the best proportion of hydrogen enriched with compressed natural gas by Warren Weaver's method and A.G.A, and established a steady state simulation model of pipeline for hydrogen enriched with compressed natural gas. After investigating those problems of major losses in the transportation process and the influence on the performance of compressors, the sources put forward corresponding suggestions for reconstruction of existing pipeline for hydrogen enriched with compressed natural gas, providing the theoretical reference for the design and construction of pipeline for hydrogen enriched with compressed natural gas.